\u25c6 Population projections for Lakshadweep and the Andaman & Nicobar Islands.
\u25c6 Based on the report \u201cUnravelling India\u2019s demographic future: 2021\u20132051.\u201d
\u25c6 Prepared by International Institute of Migration and Development (IIMAD) and the Population Foundation of India (PFI).<\/p>\n\n\n\n
\u27a4 Total population: 67,642 (2016) \u2192 74,194 (2051) (+9.68%)
\u27a4 Males: 34,716 \u2192 37,785
\u27a4 Females: 32,926 \u2192 36,319<\/p>\n\n\n\n
\u27a4 Total population: 3,98,310 (2016) \u2192 4,21,135 (2051) (+5.73%)
\u27a4 Males: 2,13,467 \u2192 2,26,139
\u27a4 Females: 1,84,843 \u2192 1,94,996<\/p>\n\n\n\n
\u25cf Smaller States\/UTs show inconsistent and erratic decadal growth, making traditional demographic projections unreliable.
\u25cf Sample Registration System (SRS) data gaps further complicate projections.
\u25cf Hence, the report uses:
\u2003\u25aa Logistic curve-fitting methods
\u2003\u25aa Mathematical modelling to generate more stable long-term projections.<\/p>\n\n\n\n
\u2726 Census of India
\u2726 Sample Registration System (SRS)
\u2726 National Family Health Survey (NFHS)
\u2726 Civil Registration System (CRS)
\u2726 National Sample Survey (NSS)<\/p>\n\n\n\n
\u25ba Helps policymakers understand demographic shifts in remote island territories. \u2022 Pancreatic cancers grow in low-oxygen (hypoxic<\/strong>) environments. \u2022 Hypoxia increases the migration<\/strong> of pancreatic cancer cells by altering their lipid composition<\/strong> and mechanical properties<\/strong>.<\/p>\n\n\n\n \u2022 The plasma membrane\u2019s lipid mix controls stiffness, flexibility, and the cell\u2019s ability to change shape. \u2022 Hypoxia reduces cortical stiffness<\/strong> (lower actin content). \u2022 Hypoxia increases cortical stiffness<\/strong> (opposite of PANC-1). \u2022 Despite different strategies, both cell types become more migratory<\/strong> under hypoxia.<\/p>\n\n\n\n \u2022 Cancer cells can actively restructure their membranes<\/strong> to adapt to hypoxic stress. \u2022 Study how hypoxia affects membrane properties in other cancer types<\/strong>. Demographic forecast of Lakshadweep Islands and A&N Islands 1. Context \u25c6 Population projections for Lakshadweep and the Andaman & Nicobar Islands.\u25c6 Based on the report \u201cUnravelling India\u2019s demographic future: 2021\u20132051.\u201d\u25c6 Prepared by International Institute of Migration and Development (IIMAD) and the Population Foundation of India (PFI). 2. Key Findings Lakshadweep \u27a4 Total population: 67,642 (2016) […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[592],"tags":[595,222,21,22,593,594,31,596,221],"class_list":["post-6740","post","type-post","status-publish","format-standard","hentry","category-short-notes","tag-an-island","tag-bank-exams","tag-competitive-exams","tag-current-affairs","tag-demographic-forecast","tag-lakshadweep-island","tag-mcq","tag-pancreatic-cancer","tag-rrb-exams"],"_links":{"self":[{"href":"https:\/\/mehnatt.com\/index.php?rest_route=\/wp\/v2\/posts\/6740","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mehnatt.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mehnatt.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mehnatt.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mehnatt.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6740"}],"version-history":[{"count":4,"href":"https:\/\/mehnatt.com\/index.php?rest_route=\/wp\/v2\/posts\/6740\/revisions"}],"predecessor-version":[{"id":6790,"href":"https:\/\/mehnatt.com\/index.php?rest_route=\/wp\/v2\/posts\/6740\/revisions\/6790"}],"wp:attachment":[{"href":"https:\/\/mehnatt.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6740"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mehnatt.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6740"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mehnatt.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6740"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\u25ba Useful for planning infrastructure, healthcare, education, and resource management<\/strong>.
\u25ba Indicates moderate but steady growth<\/strong>, important for environmental and development considerations in ecologically sensitive islands.<\/p>\n\n\n\n
\n\n\n\nPancreatic Cancer thrives in low oxygen – IIT Bombay<\/h3>\n\n\n\n
Why this research matters?<\/h4>\n\n\n\n
\u2022 Hypoxia is known to worsen cancer behaviour, but its effect on cell membranes<\/strong> was unclear.
\u2022 Membrane properties influence how easily cancer cells move and metastasise<\/strong>.<\/p>\n\n\n\nMain discovery<\/h4>\n\n\n\n
What the researchers found?<\/h4>\n\n\n\n
1. Hypoxia reshapes the membrane lipidome<\/h5>\n\n\n\n
\u2022 Under hypoxia, cells modify lipids to stay flexible and mobile<\/strong>.<\/p>\n\n\n\n2. Two pancreatic cancer cell lines show different responses<\/h5>\n\n\n\n
PANC-1<\/h5>\n\n\n\n
\u2022 Stiffening lipids are moved inward<\/strong> to organelles.
\u2022 Plasma membrane stays more fluid and malleable<\/strong>, allowing easier migration.<\/p>\n\n\n\nCAPAN-2<\/h5>\n\n\n\n
\u2022 Cells add more membrane material<\/strong> to the surface to remain flexible.
\u2022 Some stiffening lipids increase in the membrane, but only locally<\/strong>, so overall flexibility is maintained.<\/p>\n\n\n\nKey insight<\/h5>\n\n\n\n
Why this is important?<\/h4>\n\n\n\n
\u2022 Hypoxia triggers physical changes (stiffness, fluidity, lipid shifts) that support metastasis<\/strong>.
\u2022 Understanding these changes may help develop membrane-targeted anti-cancer therapies<\/strong>.<\/p>\n\n\n\nFuture directions<\/h4>\n\n\n\n
\u2022 Use solid-state NMR<\/strong> to measure how lipid packing and membrane order change under hypoxia.<\/p>\n\n\n\n
\n","protected":false},"excerpt":{"rendered":"